Mello Magnesium

The Best Magnesium Supplements of 2021

What makes Mellö the best? It’s simple.

The secret’s in the Superblend: 3 highly absorbable forms of magnesium, plus powerful amino acids, lemon made citric acid, and 72 trace minerals sourced sustainably off the Irish coast.

Tested and certified by a third-party laboratory.


3 Most Absorbable Forms of Magnesium

Mellö is a full spectrum magnesium supplement that blends three of the most bioavailable and absorbable forms of chelated magnesium to ensure the widest range of whole body benefits.

Why? Because there is no point to taking a supplement that passes straight through you before your cells can use it.


Magnesium Lactate Gluconate

Magnesium lactate gluconate is the magnesium salt of lactic acid and gluconic acid. As its name suggests it combines the benefits of magnesium lactate and magnesium gluconate into one form.

Magnesium gluconate is the salt formed by combining magnesium with gluconic acid. It demonstrates the highest oral bioavailability of magnesium salts and is recommended for treating magnesium deficiency.

Magnesium lactate is a salt formed by binding magnesium with lactic acid. Lactate is a compound naturally produced by the body for various purposes, many of which are related to wakefulness, arousal, and energy production. It has been found to prevent excitotoxicity by inhibiting excess neuronal activity and can be used as a source of energy.


Magtein® Magnesium L-threonate

Magnesium L-threonate is a form of chelated magnesium that combines magnesium with threonic acid. The only form of magnesium shown to increase intracellular magnesium levels in nerve cells, or neurons, it was developed and patented by MIT scientists for its unique ability to cross the blood-brain barrier and increase brain magnesium levels.

Recent results from a human clinical trial show the efficacy of magnesium L-threonate in restoring cognitive abilities in older adults. Animal studies have also linked this form of magnesium to various brain and nervous system benefits including memory and learning enhancements.

Magnesium is a key signaling molecule for controlling synaptic density, which determines cognitive ability and is an indicator of how well your nerve cells can communicate. Because synapses allow neurons to talk to each other, lower synaptic density and synaptic loss are associated with sensory, motor, and cognitive impairments.

Building on animal research, a 2016 study of human neuronal stem cells found that magnesium L-threonate upregulated synaptic density. This effect was attributed to the actions of threonate, which is naturally present in cerebrospinal fluid and directly induces an increase in intracellular magnesium concentrations.

Magnesium deficiency has been found to stimulate the production of tumor necrosis factor-alpha (TNF-α), the same inflammation inducing compound that is involved in Alzheimer’s disease, rheumatoid arthritis, and other inflammatory conditions.

Studies show that magnesium L-threonate can inhibit TNF-α expression by restoring levels of magnesium in glial cells. Glial cells are important because, among other life sustaining functions, their job is to make new brain cells.

Magnesium L-threonate has also been demonstrated to increase magnesium levels in cerebrospinal fluid, which in mouse models of Parkinson’s disease led to decreases in motor deficits and dopamine neuron loss.


Aquamin Magnesium Citrate

Aquamin-Mg, or Aquamin Magnesium Citrate is a natural magnesium source derived without coastal impact from the clean waters off the Irish coast. It contains 72 additional trace minerals and is bound to citric acid for enhanced bioavailability and absorption.

Magnesium citrate supports healthy digestion and regularity by causing the intestines to release water into the stool. This softens the stool helping to relieve constipation. As such, it is a common ingredient in many laxatives.

Mellö contains just enough magnesium citrate to promote regularity and healthy digestion without causing undesired laxative effects.

Magnesium citrate also helps regulate calcium transport across cell membranes and is commonly used to prevent arrhythmia because it causes artery walls to be more flexible thereby reducing the risk.


2 Powerful Amino Acids

Mellö blends the amino acids l-Theanine and gamma-Aminobutyric acid (GABA) to promote enhanced cognitive performance, immune function and relaxation.


l-Theanine is an amino acid found in tea leaves. Research suggests it may have a wide range of health benefits including enhanced mental focus and cognitive performance, better sleep, improved immune system function, and increased relaxation without drowsiness.

l-Theanine has also been shown to have positive effects on nutrient absorption and transport such as the ability to regulate glucose, lipid, and protein metabolism.


Gamma-Aminobutyric acid, or GABA, is an amino acid naturally produced by the body. It’s various roles include acting as an inhibitory neurotransmitter and a mediator of the endocrine system.

GABA is an inhibitory neurotransmitter in the brain and nervous system, which means that it suppresses or quiets down neuronal activity to promote rest, relaxation and healthy sleep. It produces natural calming effects by attaching to GABA receptor proteins. This can help with feelings of stress, anxiety, fear or restlessness.

Research also suggests that GABA acts as an endocrine mediator that influences a diverse array of gastrointestinal tract (GI) functions including intestinal motility, gastric acid secretion, lower esophageal relaxation as well as the inhibition of GI carcinogenesis and tumor growth.

Citric Acid from Lemons

Citric acid is a weak acid that plays various important roles in the body. Naturally found in coffee, lemons, and other citrus fruits, citric acid is an alkalizing agent that makes the urine less acidic, acts as an antioxidant to combat free radical damage, and enhances the absorption of minerals in the body.

Perhaps most importantly, citric acid is essential to metabolism and energy production. A central component of the citric acid cycle, a.k.a. the Krebs cycle, citric acid is a driver of cellular respiration and enables the chemical reaction responsible for metabolizing food into energy.

Unlike common products on the market Ned does not use lab made citric acid which is created by black mold, Aspergillus niger as it feeds on sugar. The citric acid in Mellö is naturally sourced from lemons.

72 Trace Minerals

Trace minerals are those which the human body needs in tiny amounts to perform vital functions. These include synthesizing hormones, metabolizing food, regulating blood sugar levels, building bone and cartilage, preventing tooth decay, wound healing, immunity and every other major function in your body.